Recent developments in the cell biology of basic fibroblast growth factor.
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منابع مشابه
Recent developments in the cell biology of basic fibroblast growth factor
I N the past four years there has been an enormous increase in research involving basic fibroblast growth factor (FGF) t as a result of the development of effective methods for the isolation of the protein and the availability of characterized nucleic acid probes, specific antibodies, and recombinant growth factor. Several reviews have been published describing much of the basic biology of acid...
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The int-2 protein is related to basic fibroblast growth factor (bFGF) by amino acid sequence homology. To assess its biological activity, we constructed retroviral vectors containing four variants of mouse int-2 complementary DNA under the transcriptional control of the beta-actin promoter and tested their effects on human SW13 adrenal cortical tumor cells. This cell line specifically requires ...
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BACKGROUND Topical silicone gel has shown promise in the treatment of hypertrophic and keloid scars. However, its mechanism of action remains undetermined. OBJECTIVE To investigate whether the presence of silicone alters the secretion of basic fibroblast growth factor (bFGF), a key cytokine involved in the scar formation process. DESIGN Serum-free fibroblast cell cultures were established f...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1989
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.109.1.1